Event Start



About the Masterclass

The Hedenstierna Laboratory MasterClass symposium is an academic meeting dealing with physiological mechanisms relevant to intensive care and anaesthesia. It was established in 2011 to honour the life-time scientific achievement of Professor Göran Hedenstierna and it has gained a reputation for its quality. It is traditionally composed of two meeting days. The first day is open to registered participants during which high profile scientists present state of the art knowledge about the masterclass topics. Then the speakers are asked to engage in discussions with each other and with the audience. Panel discussions are part of the program. The audience comprises both young and senior specialist in anaesthesia and intensive care who are eager to keep abreast with recent findings. This year the theme of the symposium is: "A physiological approach to Circulatory Failure". The brochure of the web edition of October 2024 of the Masterclass can be dowloaded by clicking here.




The Hedenstierna Laboratory annual brainstorming

During the day before the symposium is organized the traditional annual brainstorming. The different research groups that compose the Hedenstierna Laboratory together with the scientists that form the international network of researchers using the infrastructures of the laboratory, offer presentations of their state-of-the-art research. Around the table sit together young and senior scientists, including the speakers and the moderators of the symposium. The time frame of the presentations is organized to allow elaborate and open discussions, with direct and frank questions in a pure scientific spirit. The attendance is subjected to personal invitation.



25 October
2024

Uppsala
Sweden

Large
Audience

Six
Outstanding
Speakers

(photo by Mikael Wallerstedt)





Program of the Symposium 2024

Explore the program of the Symposium by clicking on the tabs of the single sessions or download the pdf file by clicking HERE.
9:00 - 9.20

9.20-9.30


Welcome address

Miklós Lipcsey, Gaetano Perchiazzi, Christian Rylander

Chairs: Andrea Kollmann and Gaetano Perchiazzi

9.30 – 10.10


Should I care about a blood pressure drop during anaesthesia?

Michelle Chew
Linköping, Sweden
10.10 - 10.50


Noradrenalin and shock: one recipe for all?

Olfa Hamzaoui
Reims, France
10.50 - 11.00


Short Break

Chairs: Maria Bergquist and Robert Frithiof

11.00 - 11.30


Microcirculation PRO: Why I resuscitate mitochondria and not persons

Mervyn Singer
London, UK
11.30 - 12.00


Microcirculation CON: Why I resuscitate persons and not mitochondria

Michelle Chew
Linköping, Sweden
12.00 - 12:10


Discussion on resuscitation and microcirculation

Auditorium invited to discussion
12.10 - 13.00


LUNCH

Chairs: Stephanie Franzén and Carl-Henrik Ölander

13.00 - 13.40


Is there evidence for invasive hemodynamic monitoring?

Xavier Monnet
Paris, France
13.40 – 14.20


Fluid therapy in presence of RV dysfunction?

Jean-Louis Teboul
Le Kremlin Bicêtre, France
14.20 – 14.50


COFFEE

Chairs: Mariangela Pellegrini and Miklós Lipcsey

14.50 - 15.30


Fluids after fluids: the dilemma of the post-resuscitation phase

Manu Malbrain
Oudenaarde, Belgium
Lublin, Poland
15.30 - 16.10


Will septic cardiomyopathy develop in your patient?

Mervyn Singer
London, UK

Chair: Christian Rylander

16.10 – 16.30


Take home messages

Panel Discussion
13.00-16.00

Attendance is subject to personal invitation.
The different research groups that compose the Hedenstierna Laboratory together with the scientists that form the international network of researchers using the infrastructures of the laboratory, offer presentations of their state-of-the-art research. Around the table sit senior and junior researchers, showing without any constraint the results of their most recent research. The format is an open, friendly and constructive brainstorming.


PREVIOUS EDITIONS OF THE HEDENSTIERNA MASTERCLASS SYMPOSIUM



Year 2011. Theme: What's new in the management of ARDS?
A LarssonIs the ARDS definition useful?
JB BorgesImaging strategies in laboratory
F SipmannMonitoring strategies at bedside
G HedenstiernaAbdominal consequences of respiratory management in ARDS
L GattinoniManagement of ARDS: the Italian approach
M AmatoManagement of ARDS: the Brazilian approach
L BrochardManagement of ARDS: the French approach
L Gattinoni, M Amato, L BrochardItalian, Brazilian and French consensus?
.
.
.
Year 2012. Theme: A physiological approach to fluid therapy in critical illness
R HahnFluid therapy; dynamics and kinetics
PO GrändeMechanisms of edema formation
M PinskyMonitoring fluid therapy and edema formation
PO GrändeFluid therapy optimization for different target organs: the brain
R FrithiofFluid therapy optimization for different target organs: the kidneys
R HubmayrFluid therapy optimization for different target organs: the Lungs I
P RoccoFluid therapy optimization for different target organs: the Lungs II
.
.
.
Year 2013. Theme: A physiological approach to sepsis in intensive care
O Cars The threat of antibiotic resistance for patients with severe infections
T Tängden How to kill Gram-negative superbugs
M Givskov Quorum sensing as an antimicrobial target
JL VincentSepsis seen from the host’s viewpoint: The heart and circulation
M LipcseySepsis seen from the host’s viewpoint: The innate immune system response and the endothelium
A SlutskySepsis and ARDS: What are the links?
C RoncoSepsis seen from the host’s viewpoint: the kidneys
.
.
.
Year 2014. Theme: A physiological approach to lung recruitment and PEEP
G HedenstiernaLung collapse during anesthesia
J MariniLung collapse/edema in early and late ARDS
JB Borges Lung collapse and ventilator induced lung injury
M AmatoThe underlying mechanisms of lung recruitment and PEEP
F Suarez SipmannThe circulatory effects of lung recruitment and PEEP
J PeterssonThe effects of prone positioning
G Tusman Clinical experience using lung recruitment maneuvers during anesthesia
O StenqvistLung recruitment: Who is a responders and who is not?
.
.
.
Year 2015. Theme: A physiological approach to extracorporeal techniques in the ICU
A PesentiExtracorporeal carbon dioxide removal
K PalmerExtracorporeal oxygenation-ECMO
K Nagao Extracorporeal assist at cardiopulmonary resuscitation
P Schiller Extracorporeal assist at heart failure
J Wendon Extracorporeal assist in severe liver failure
M Lipcsey Extracorporeal endotoxin absorption
M Super Artificial extracorporeal spleen using mannose binding lectin absorption
.
.
.
Year 2016. Theme: A physiological approach to Brain Function in Anaesthesia and Intensive Care
G van der BergheMetabolic effects on the brain during critical illness and surgery
D AnnanePathophysiological mechanisms in septic encephalopathy
M OddoMultimodal monitoring of cerebral function in the ICU
C SinderbyThe brain stem and respiratory drive during critical illness
F LennmyrNeuroprotection during CPR
G LiljaLong term effects on the brain from cardiac arrest
L I ErikssonEffects from anaesthesia and surgery on cognitive function
E S WilcoxEffects from ARDS on the brain
.
.
.
Year 2017. Theme: A physiological approach to The Sick Child in Anaesthesia and Intensive Care
R SindelarNeonatal delivery room emergencies you need to master
K BeckePediatric airway management -current advances and future developments
B FaurouxUtility of oesogastricpressure measurements in children with respiratory failure and alternatives for ventilatorysupport
B KavanaghVentilator Induced Lung Injury in children and how to avoid it
H WinbergDrowning in children -can we predict outcome?
L VutskitsLong term effects on the young brain by anesthesia and surgical stress
W HabreAnaesthesiaPractice In Children Observational Trial: The APRICOT study and beyond
.
.
.
Year 2018. Theme: A physiological approach to Monitoring in Anaesthesia and Intensive Care
G StemmeHow advances in microtechnology can be used for minimal invasive healthcare
M ChewEchocardiography: pitfalls and interpretation
F Suarez SipmannMonitoring of the lung function, from spirometry to PET
DG BatesModelling different states and interventional effects within the lung
M OstermannMonitoring the kidney
J HästbackaMonitoring inflammation
E BrownMonitoring of the Human Brain
.
.
.
Year 2019. Theme: A physiological approach to Artificial Ventilation
A Larsson My life so far: from the Ambu balloon to synchrotron radiation computed tomography
P WagnerMechanical ventilation through the eyes of a physiologist: does it really improve gas exchange?
J LaffeyWhat happens under the hood? Lessons of translational medicine about ARDS and ventilation
JW KronishOptimizing intraoperative atelectasis may change perioperative outcomes?
P PelosiStrain, energy, power. The story on how physics invaded clinical ventilation
C GuerinLooking at ventilation in three dimensions: flip the lung and rescue the patient
A PesentiDoes the patient really know what is best? The breakthrough of self-induced lung injury
.
.
.
Year 2020. Suspended for the pandemics
.
.
.
Year 2021. Theme: A physiological approach to Covid-19: Lessons from a pandemic
P Pelosi Aeration and perfusion in ARDS and COVID-19: the dark side of the moon
S EinavCOVID-19 and intensive care: the challenges posed by pregnancy
C GuerinPut them prone! Physiology and clinics of a pandemic leitmotif
M OstermannCOVID-19 between the lung and the kidney: progression and outcome in critically ill patients
E GoligherShall they breath or not? The fate of the diaphragm during Covid-19 and after
.
.
.
Year 2022. Theme: A physiological approach to Imaging and Interventions in Anesthesia and Intensive Care Medicine
G Kuchcinski Functional MRI in traumatic brain injury
J WikströmMRI to evaluate cerebral perfusion and metabolism
D LindströmDiagnosis and interventions in aortic pathologies
M ChewUltrasonographic assessment of the circulation
C KabrhelCatheter directed interventions for acute pulmonary embolism
T MudersEIT to assess pulmonary ventilation and perfusion
T GranbergThe future of imaging: MRI and PET
.
.
.
Year 2023. Theme: A physiological approach to Respiratory Failure
K Vaporidi How to assess respiratory drive
G Perchiazzi Is Patient Self-Induced Lung Injury a clinically relevant risk?
A Vieillard-Baron How to detect and manage heart-lung interactions in the ventilated patient
M Jonsson Fagerlund What is an acceptable lower limit of oxygenation during anaesthesia?
C Meyhoff Is there an injurious hyperoxia during anesthesia?
J Laffey Are there pharmacological or anti-inflammatory strategies that work?
D Battaglini Why should I treat different phenotypes differently?
.
.
.
Year 2024. Theme: A physiological approach to Circulatory Failure
M Chew Should I care about a blood pressure drop during anaesthesia?
O Hamzaoui Noradrenalin and shock: one recipe for all?
M Singer Microcirculation PRO: Why I resuscitate mitochondria and not persons
M ChewMicrocirculation CON: Why I resuscitate persons and not mitochondria
X Monnet Is there evidence for invasive hemodynamic monitoring?
JL Teboul Fluid therapy in presence of RV dysfunction?
M Malbrain Fluids after fluids: the dilemma of the post-resuscitation phase
M Singer Will septic cardiomyopathy develop in your patient?